How to Microdose Psilocybin
In the psychedelic community, microdosing psilocybin means consuming a very small dose of psilocybin mushrooms every third or fourth day. Typical doses range from 0.10 grams to 0.25 grams of dried P. cubensis mushrooms. Most users will pulverize the mushrooms into a powder, weigh out doses, then store those doses in size 00 capsules for later use.
Paul Stamets created a unique microdosing technique he calls “stacking.” It involves a combination of niacin, Lions Mane, and P. cubensis. This method combines approximately 0.1-1 gram of P. cubensis, 5-20 grams of Lions Mane, and 101-200 milligrams of niacin. His belief is the niacin enhances the effects of the psilocybin while reducing the psychedelic experience. Buy 500mg Psilocybin Microdose
How Psilocybin Works inside the Body|Buy 500mg Psilocybin Microdose
Psilocybin is a serotonergic substance meaning it acts on the serotonin, or 5-hydroxytryptamine, receptors in the central and peripheral nervous system. The primary receptors it acts upon are the 5-HT2B and 5-HT2C receptors. It also activates the 5-HT2A receptors with slightly lower activity. The activity at these receptors causes an increased concentration of dopamine at the basal ganglia. This is responsible for the euphoric and psychedelic effects of psilocybin.Buy 500mg Psilocybin Microdose
Small doses of psilocybin, referred to as a “microdose,” do not produce any acute effects, but rather a psychological and social benefit from regularly consuming microdoses. These effects include increases in:
- Alleviated symptoms of depression and anxiety
- Enhanced productivity
- Improvements in overall well-being
- Enhancements in convergent and divergent thinking
When consumed in large doses, psilocybin produces a profound psychedelic effect involving:
- Closed and open eye visuals
- Dilated pupils
- Reduced appetite
- Heightened emotions
- An altered sense of reality.
Common Interactions when Microdosing Psilocybin
Psilocybin, along with most other psychedelics, causes vasoconstriction. This means mixing it with other vasoconstrictors can cause unpleasant and potentially dangerous effects. Mixing psilocybin with any MAOIs can enhance its potency which could cause a microdose to produce stronger effects than expected. Alcohol mixed with psilocybin mushrooms can place unnecessary stress on the liver since they are both metabolized by it.